Globus Pallidus Stimulation Reduces Frontal Hyperactivity in Tardive Dystonia
نویسندگان
چکیده
منابع مشابه
Globus pallidus deep brain stimulation in dystonia.
Globus pallidus deep brain stimulation (GPi-DBS) is a useful alternative in the treatment of dystonia. Patients selected for GPi-DBS were prospectively rated with the Unified Dystonia Rating Scale (UDRS). Also, "blinded" videotape assessments were performed. Eleven patients were identified. Compared with pre-DBS scores, there were improvements in mean total UDRS score (15.3%) and in the followi...
متن کاملBilateral deep brain stimulation of the globus pallidus to treat tardive dyskinesia.
CONTEXT Tardive dyskinesia (TD) is a common and potentially disabling disorder induced by use of antipsychotic drugs for which medical treatment often gives disappointing results. OBJECTIVE To assess the efficacy of bilateral deep brain stimulation of the internal part of the globus pallidus to treat severe TD. DESIGN Prospective phase 2 multicenter study. SETTING Six French university ho...
متن کاملAbnormal activity in the globus pallidus in off-period dystonia.
Pallidotomy was performed in a parkinsonian patient with off-period foot dystonia. Dystonia appeared at the beginning of surgery and disappeared after the first microelectrode penetration of the globus pallidus, perhaps a micropallidotomy effect. Neuronal recording during dystonia revealed that the mean firing rates were low in both the internal and external segments of the globus pallidus, and...
متن کاملDeep brain stimulation electrode used for radiofrequency lesion of the globus pallidus internus in dystonia.
BACKGROUND There have recently been increasing case reports in the literature of deep brain stimulation (DBS) electrodes used for lesioning with satisfactory clinical success in the treatment of Parkinson disease and tremor. METHODS After preliminary experiments of radiofrequency (RF) lesioning with a quadripolar DBS lead, a paediatric case of generalized primary dystonia was treated by RF le...
متن کاملBilateral deep-brain stimulation of the globus pallidus in primary generalized dystonia.
BACKGROUND Severe forms of dystonia respond poorly to medical treatment. Deep-brain stimulation is a reversible neurosurgical procedure that has been used for the treatment of dystonia, but assessment of its efficacy has been limited to open studies. METHODS We performed a prospective, controlled, multicenter study assessing the efficacy and safety of bilateral pallidal stimulation in 22 pati...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 2008
ISSN: 0271-678X,1559-7016
DOI: 10.1038/sj.jcbfm.9600610